N1-Headache is for people with frequent migraine attacks who would like to scientifically answer this question: How do my personal lifestyle factors and medications affect my migraine attacks?
1. Who should use N1-Headache?
N1-Headache connects people with migraine to their clinicians through a mobile app and web-based dashboard. It requires you to log information about your headaches, migraine symptoms and medication use on days you have an attack, and track a range of factors (moods, weather, diet, etc.) on a daily basis that may influence your risk of attack. After you have recorded data for a minimum of 90 days, your results are processed, analyzed, and delivered as a set of three maps: Individual Trigger Map™, Individual Protector Map™ and No Association Map.™ (Click any of the features that are underlined to learn more.) The maps are incorporated within a Personal Analytical Report that you may print out as a PDF and share with your healthcare provider.
N1-Headache is the only app that doesn’t ask people with migraine to guess the behavioral and lifestyle factors that are associated with their attacks. It is the first digital health platform to apply N of 1 analytics to personalize management of migraine.
All of the results you receive from N1-Headache come from your individual data. It gives you and your clinician the opportunity to develop a highly personalized treatment plan. You can then experiment with behavioral and medication changes and track their impact on your migraine outcomes.
2. Visual Migraine Language™ (VML2)
VML is a set of visual icons that represent more than 70 potential migraine attack risk factors and associated symptoms. N1-Headache developed VML to make your daily tracking quicker and easier. iOS users may click any of the VML icons within the app to learn more about them.
3. Daily Tracking & Reminder
Tracking every day improves the ability of N1-Headache’s analytical engine to identify factors associated with your migraine days and your migraine-free days.
Not to worry, you can simply fill in the day you missed for up to 48 hours. Note that you can only enter missing data from the previous two days.
By restricting data entry to just the last two days missed, the results of your tracking will be more accurate.
To reduce the risk of missing a day of tracking, you can use the daily reminder function. Incorporating tracking into your daily routine can help you form a habit, which will make tracking easier and faster.
Absolutely! This will improve the accuracy of your results, enabling N1-Headache to identify the everyday things that are associated with your migraine attacks as well as those that are not.
Yes, you should track every day. Daily data helps N1-Headache accurately identify the factors that can increase, decrease and have no effect on your migraine attacks.
N1-Headache is the only app that determines if your headache is a migraine or other type of headache from the symptoms you enter, based on criteria defined by the International Classification of Headache Disorders (ICHD-3) Guidelines.
4. Customizing Daily Factors
These are the everyday things that may be associated with risk of a migraine attack. They are organized into groups of modules:
• Warning Signs(Premonitory Symptoms)
• Lifestyle habits
• Recreational Drugs
• Gender - specific factors
5. Time-period Comparison
This tool allows you to compare the number, severity, and duration of your headaches and migraine attacks between two different periods of time.
6. Medication Overuse Alert
This alert warns of your risk of medication overuse. It calculates your current risk of medication overuse based on ALL of the medications you are taking to treat your migraine attacks.
Only available if you have enrolled through the N1 - Headache Clinician Program.
You and your healthcare provider will receive an alert by email advising of your risk of medication overuse. If you receive a medication overuse alert, you will be instructed to contact your healthcare provider to discuss what you should do.
No, it will not, however, it will provide an opportunity for you and your healthcare provider—who also receives the alert— to monitor your medication use, assess your risk of medication overuse, and identify the potential need to change your therapy.
7. Interpreting Individual Maps
• Suspected Trigger Map™
• Trigger Map™
• Protector Map™
• No Association Map™
• Insufficient Data Map
N1 - Headache presents your results in a series of visual formats that resemble targets.Risk factors with the strongest association to migraine attacks appear closer to the center; weaker associations appear further away.
Your Individual Trigger, Protector, No Association and Insufficient Data maps show the results of your personal analysis after a minimum of 90 days tracked data. While the Suspected Trigger Map data is not part of your formal analysis, you should compare your results to the risk factors you initially identified as suspected migraine attack triggers.
This is a map based on what you think your triggers are. The map displays the factors that you have identified as potential migraine triggers.
That’s okay, but if you suspect even one, you should enter it. For example, if you suspect a trigger to be strong odors, you can check to see if this is true after 90 days of tracking.
This map shows factors associated with an increased risk of migraine attack. For example, if the map shows that missing a meal is one of your migraine triggers, you may try to avoid waiting too long between meals as a way to self-manage your attacks.
Migraine protectors are factors associated with a decreased risk of migraine attack. Like migraine triggers, your migraine protectors are identified from your personal data analysis. The concept of protective factors has been pioneered by Curelator and is unique to N1-Headache.
By learning what factors decrease your risk of migraine attack, you’ll be in a better position to manage your migraine. For example, if your map shows that longer sleep duration is a migraine protector, you may opt to get more sleep as a way to self-manage your attacks.
Factors that are not associated with either an increase or a decrease in the risk of a migraine attack are identified as No Association Factors.
These are factors that don’t have enough data available to analyze, so N1-Headache cannot identify if there is an association with your migraine attacks.
If you avoid certain factors, there may not be enough data to associate risk of migraine with them. Therefore, if you completely avoid something such as chocolate during your 90 day data collection period, it may fall into the category of “insufficient data” due to lack of exposure to that factor.
Your analysis is based on how the day-to-day variations of exposure to factors may affect your migraine attacks.
For example, if you drink the same amount of coffee every single day, N1 - Headache will not be able to determine the association of coffee with your risk of migraine attacks.But, if you drink coffee very rarely, you may not have enough exposures to coffee for your analysis to determine whether coffee is associated with your attacks.
8. Understanding Your Personal Analytical Report
It provides a summary of all of the information you have entered into the N1-Headache app, including: frequency, severity and duration of your headaches and migraine attacks, along with migraine-related disability (MIDAS/PedMIDAS scores), and medication use. It also incorporates all of your individual maps.
You and your healthcare provider can use the information in your report to see how your migraine outcomes are changing and your disease is progressing over time.The report could also be helpful for securing reimbursement from your insurance company by documenting your response to preventative medications such as Botox or a CGRP inhibitor.